| Cat. No. |
Product Name |
Information |
| PC-60260 |
VUF11403
CXCR7 agonist
|
VUF11403 is a potent CXCR7 (ACKR3) agonist with pKi of 8.1 (hCXCR7), induces recruitment of β-arrestin2 and subsequent internalization of CXCR7. |
| PC-60259 |
VUF11207 fumarate
CXCR7 agonist
|
VUF11207 fumarate is a potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM, inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells. |
| PC-60244 |
(S)-CCX-777
CXCR7 agonist
|
(S)-CCX-777 is a small-molecule partial agonist of CXCR7 (ACKR3).. |
| PC-60243 |
(R)-CCX-777
CXCR7 agonist
|
(R)-CCX-777 is a small-molecule partial agonist of CXCR7 (ACKR3), the (R)-form of CCX777. |
| PC-60242 |
CCX-777
CXCR7 agonist
|
CCX-777 is a small-molecule partial agonist of CXCR7 (ACKR3). |
| PC-60240 |
CCX2553
CCR6 antagonist
|
CCX2553 is a potent and specific CCR6 antagonist. |
| PC-60212 |
CCX-771
CXCR7 inhibitor
|
CCX-771 is a potent, selective CXCR7 antagonist with IC50 of 4.1 nM. |
| PC-45710 |
Danirixin
CXCR2 antagonist
|
Danirixin (GSK1325756) is a high-affinity, selective and reversible CXCR2 antagonist (IC50=12.5 nM, CXCL8. |
| PC-47505 |
Motixafortide
CXCR4 antagonist
|
Motixafortide (BL-8040, BKT-140, TF-14016) is a 14-residue biostable synthetic peptide, high-affinity CXCR4 antagonist (IC50=1 nM). |
| PC-45771 |
TAK-220
CCR5 antagonist
|
TAK-220 (TAK220) is a potent, specific, orally bioavailable CCR5 antagonist that blocks the binding of MIP-1α to CCR5 with IC50 of 1.4 nM. |
| PC-42443 |
SCH-527123
CXCR2 antagonist
|
SCH-527123 (Navarixin, MK-7123) is a potent, selective, orally bioavailable CXCR2/CXCR1 receptor antagonist with Kd of 0.08 and 41 nM for cynomolgus CXCR2 and CXCR1, respectively. |
| PC-42417 |
CCX140
|
CCX140 (Ilacirnon, CCX140B) is a potent, selective, orally bioavailable CCR2 antagonist with Kd of 2.3 nM for hCCR2. |
