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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-LMD-009
LMD-009

Chemical Structure : LMD-009

CAS No.: 950195-51-4

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LMD-009 (LMD 009, LMD009)

货号: PC-60972Not For Human Use, Lab Use Only.

LMD-009 (LMD 009, LMD009) is a potent, selective, nonpeptide CCR8 agonist that stimulates CCR8-mediated chemotaxis, inositol phosphate accumulation and calcium release with EC50 of 11-87 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LMD-009 (LMD 009, LMD009) is a potent, selective, nonpeptide CCR8 agonist that stimulates CCR8-mediated chemotaxis, inositol phosphate accumulation and calcium release with EC50 of 11-87 nM.
LMD-009 displays no activity against other chemokine receptors.

物理化学性质&存储条件

分子量 471.601
分子式 C29H33N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

8-[3-(2-methoxyphenoxy)benzyl]-1-phenethyl-1,3,8-triaza-spiro[4.5]decan-4-one

参考文献

1. Jensen PC, et al. Mol Pharmacol. 2007 Aug;72(2):327-40.

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