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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-CX815
CX815

Chemical Structure : CX815

CAS No.: 109628-27-5

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CX815 (CX-815, NSC 120213)

货号: PC-60625Not For Human Use, Lab Use Only.

CX815 (NSC 120213) is a potent, selective CXCR2 inhibitor with IC50 of 0.4 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CX815 (NSC 120213) is a potent, selective CXCR2 inhibitor with IC50 of 0.4 nM.
CX815 displays>1,000-fold selectivity over CXCR4 (IC50>50 uM).
CX815 inhibits cell proliferation of H1299 and H460 cells with IC50 of 3.5 and 4.1 uM in MTT assays.

物理化学性质&存储条件

分子量 327.398
分子式 C18H17NO3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide

参考文献

1. Ha H, et al. J Chem Inf Model. 2015 Aug 24;55(8):1720-38.

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