| Cat. No. |
Product Name |
Information |
| PC-42391 |
IT1t dihydrochloride
CXCR4 inhibitor
|
IT1t (Isothiourea 1t) dihydrochloride is a highly potent, selective, orally bioavailable CXCR4 inhibitor with binding IC50 of 8 nM for hCXCR4, IC50 of 1.1 nM in Ca2+-mobilization assays. |
| PC-42390 |
IT1t
CXCR4 inhibitor
|
A highly potent, selective, orally bioavailable CXCR4 inhibitor with binding IC50 of 8 nM for hCXCR4, IC50 of 1.1 nM in Ca2+-mobilization assays. |
| PC-28499 |
GPR15 antagonist-1
GPR15 antagonist
|
GPR15 antagonist-1 (Compound 5) is a GPR15 antagonist (Docking Score, 10.11). |
| PC-28300 |
ATI-2341 TFA
CXCR4 agonist
|
ATI-2341 TFA is a potent, selective and allosteric CXCR4 agonist with EC50 of 194 nM. |
| PC-27093 |
LMD-902
CCR8 agonist
|
LMD-902 is a potent and selective CCR8 agonist with EC50 of 15 nM. |
| PC-27092 |
CCR8 agonist 1
CCR8 agonist
|
CCR8 agonist 1 is a potent and selective CCR8 agonist with EC50 of 8 nM, shows no agonistic or antagonistic activity for CXCR2. CXCR4, CCR2 and CCR7. |
| PC-27074 |
JNJ-17166864
CCR2 antagonist
|
JNJ-17166864 is a potent, highly selective CCR2 antagonist. |
| PC-26821 |
HF51116
CXCR4 antagonist
|
HF51116 is a potent small molecule CXCR4 antagonist with binding IC50 of 12 nM, potently mobilizes hematopoietic stem cells (HSCs) in vivo. |
| PC-24281 |
trans-VUF25471
ACKR3 agonist
|
trans-VUF25471 is a small moleculephotoswitchable atypical chemokine receptor 3 (ACKR3) agonist, can be effectively switched from its thermodynamically stable trans state to the less active cis-isomer with a photostationary state of 96%. |
| PC-24136 |
Fosrugocrixan
CX3CR1 antagonist
|
Fosrugocrixan is a potent, selective antagonist of CX3C chemokine receptor 1 (CX3CR1) with antiinflammatory activity. |
| PC-24077 |
IDOR-1136-517
CCR8 antagonist
|
IDOR-1136-5177 is a highly potent, selective CCR8 antagonist with IC50 of 2 nM (hCCR8). |
| PC-23972 |
Reparixin L-lysine salt
CXCR1/2 inhibitor
|
Reparixin L-lysine salt (Repertaxin) is a potent, selective, non-competitive allosteric inhibitor of CXCL8 receptor CXCR1 and CXCR2 activation with IC50 of 1 nM and 100 nM, respectively. |
