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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-trans-VUF25471
trans-VUF25471

Chemical Structure : trans-VUF25471

CAS No.:

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trans-VUF25471 (ACKR3 agonist trans-3e)

货号: PC-24281Not For Human Use, Lab Use Only.

trans-VUF25471 is a small moleculephotoswitchable atypical chemokine receptor 3 (ACKR3) agonist, can be effectively switched from its thermodynamically stable trans state to the less active cis-isomer with a photostationary state of 96%.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

trans-VUF25471 is a small moleculephotoswitchable atypical chemokine receptor 3 (ACKR3) agonist, can be effectively switched from its thermodynamically stable trans state to the less active cis-isomer with a photostationary state of 96%.

物理化学性质&存储条件

分子量 396.51
分子式 C23H29FN4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

trans-N-(tert-butyl)-1-(3-((4-fluorophenyl)diazenyl)benzyl)piperidine-4-carboxamide

参考文献

1. Sophie Bérenger, et al. ACS Omega. 2025 Feb 18;10(8):8675-8686.

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