| Cat. No. |
Product Name |
Information |
| PC-60620 |
SX-517
CXCR1/CXCR2 inhibitor
|
SX-517 is a potent, specific, noncompetitive dual CXCR1 and CXCR2 antagonist with IC50 of 38 nM (vs. CXCL1) and 36 nM (vs. CXCL8), respectively. |
| PC-60619 |
SX-576
CXCR1/CXCR2 inhibitor
|
SX-576 is a potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively. |
| PC-60618 |
AZD 5069
CXCR2 antagonist
|
AZD 5069 (AZD5069) is a potent, selective, slowly reversible and orally bioavailable CXCR2 antagonist that inhibits CXCL8 binding to CXCR2 with pIC50 of 9.1. |
| PC-60617 |
AZ10397767
CXCR2 antagonist
|
AZ10397767 (AZ767) is a potent, selective CXCR2 inhibitor that inhibits CXCL8 binding to CXCR2 with pIC50 of 9.0. |
| PC-60616 |
AZ 13381758
CXCR2 antagonist
|
A potent, small molecule CXCR2 inhibitor with IC50 of 26 nM and 30 nM for mCXCR2 and hCXCR2, respectively. |
| PC-60592 |
ATI-2341
CXCR4 agonist
|
ATI-2341 is a potent, allosteric CXCR4 agonist with EC50 of 194 nM. |
| PC-60339 |
PRX-177561
CXCR4 antagonist
|
PRX-177561 is a novel potent, selective, brain-penetrating, orally active CXCR4 antagonist with Ki of 3 nM. |
| PC-60325 |
JNJ-27141491
CCR2 antagonist
|
JNJ-27141491 is a potent, selective, noncompetitive, orally active CCR2 antagonist with IC50 of 172 nM. |
| PC-60324 |
BMS-22
CCR2 antagonist
|
BMS-22 is a potent, selective, allosteric CCR2 antagonist with binding IC50 of 5.1 nM. |
| PC-60323 |
CCR2-RA-[R]
CCR2 antagonist
|
CCR2-RA-[R] is a potent, selective, allosteric CCR2 antagonist with IC50 of 103 nM. |
| PC-60322 |
BMS-687681
CCR2/5 inhibitor
|
BMS-687681 (BMS-681) is a potent and orally bioavailable dual antagonist of CCR2 and CCR5 with binding IC50 of 0.7 nM and 2.4 nM, respectively. |
| PC-60261 |
Chalcone 4 hydrate
CXCL12 inhibitor
|
Chalcone 4 hydrate is a potent, selective inhibitor of CXCL12 binding to CXCR4 and CXCR7 with IC50 of 200 nM. |
