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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-GSK 163929
GSK 163929

Chemical Structure : GSK 163929

CAS No.: 716354-04-0

GSK 163929 (GSK163929;GSK-163929)

货号: PC-61090Not For Human Use, Lab Use Only.

GSK 163929 is a potent, selective CCR5 antagonist and HIV-1 entry inhibitor with pIC50 of 8.37 and 8.46 in HOS and PBL assays, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GSK 163929 is a potent, selective CCR5 antagonist and HIV-1 entry inhibitor with pIC50 of 8.37 and 8.46 in HOS and PBL assays, respectively.

    物理化学性质&存储条件

    分子量 696.255
    分子式 C36H40ClF2N5O3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-chloro-2-fluoro-5-(4-(3-fluorophenyl)-4-(2-((1R,3r,5S)-3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)piperidine-1-carbonyl)-N-methylbenzenesulfonamide

    参考文献

    1. Kazmierski WM, et al. J Med Chem. 2011 Jun 9;54(11):3756-67.

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