FAUC 1104 | CXCR3 agonist | Probechem Biochemicals

Chemical Structure : FAUC 1104

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FAUC 1104 (FAUC1104, FAUC-1104)

货号: PC-61171Not For Human Use, Lab Use Only.

FAUC 1104 is a potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins, induces chemotaxis, but fails to induce receptor internalization or β-arrestin 2 recruitment.

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FAUC 1104 is a potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins, induces chemotaxis, but fails to induce receptor internalization or β-arrestin 2 recruitment.

物理化学性质&存储条件

分子量	774.959
分子式	C46H54N4O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-Butyl {(S)-1-[(2,2-diphenylethyl)amino]-6-[(S)-2-(4-(4-methoxyphenyl)-4-oxobutanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido]-1-oxohexan-2-yl}carbamate

参考文献

1. Milanos L, et al. J Med Chem. 2016 Mar 10;59(5):2222-43.

FAUC 1104 (FAUC1104, FAUC-1104)

生物&药学活性

物理化学性质&存储条件

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FAUC 1104 (FAUC1104, FAUC-1104)

生物&药学活性

物理化学性质&存储条件

参考文献

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