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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-Balixafortide
Balixafortide

Chemical Structure : Balixafortide

CAS No.: 1051366-32-5

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Balixafortide (POL6326;POL-6326)

货号: PC-61293Not For Human Use, Lab Use Only.

Balixafortide (POL6326) is a potent, selective, peptidic CXCR4 antagonist that interferes with the tumor-protective microenvironment and sensitizes tumor cells to chemotherapy.

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5 mg ￥1680 In stock
10 mg ￥2580 In stock
25 mg ￥4580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Balixafortide (POL6326) is a potent, selective, peptidic CXCR4 antagonist that interferes with the tumor-protective microenvironment and sensitizes tumor cells to chemotherapy.
Balixafortide (POL6326) induces efficient mobilization of HSPCs (hematopoietic stem and progenitor cell) in clinical trails.

物理化学性质&存储条件

分子量 1782.029
分子式 C80H112N22O21S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ala-cys-ser-ala-pro-arg-tyr-cys-tyr-gln-lys-pro-pro-tyr-his cyclic (2->9)-disulfide

参考文献

1. Karpova D, et al. J Transl Med. 2017 Jan 3;15(1):2.

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