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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-NVP-BDZ 824
NVP-BDZ 824

Chemical Structure : NVP-BDZ 824

CAS No.: 916306-04-2

NVP-BDZ 824 (NVP-BDZ824;BDZ 824)

货号: PC-61173Not For Human Use, Lab Use Only.

NVP-BDZ 824 is a potent, highly selective antagonist of chemokine receptor CXCR3 with binding IC50 of 146 nM, Ca2+-mobilization IC50 of 28 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NVP-BDZ 824 is a potent, highly selective antagonist of chemokine receptor CXCR3 with binding IC50 of 146 nM, Ca2+-mobilization IC50 of 28 nM.

    物理化学性质&存储条件

    分子量 442.563
    分子式 C27H30N4O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (6aR,9R)-N9,N9-diethyl-N7-(o-tolyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide

    参考文献

    1. Thoma G, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6185-8.

    2. Bernat V, et al. ChemMedChem. 2012 Aug;7(8):1481-9.

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