| Cat. No. |
Product Name |
Information |
| PC-21011 |
KAND567
CX3CR1 inhibitor
|
Rugocrixan (KAND567, AZD8797) is a potent, selective and orally available C-X3-C motif chemokine receptor 1 (CX3CR1, fractalkine receptor) antagonist with binding Ki of 3.9 nM (human CX3CR1), 720-fold selectivity over CXCR2. |
| PC-20971 |
CCR7 inhibitor 30c
CCR7 inhibitor
|
CCR7 inhibitor 30c is a potent, selective CC chemokine receptor 7 (CCR7) antagonist with IC50 of 0.43 uM, 25-fold selectivity over CXCR2. |
| PC-20802 |
SCH-479833
CXCR1/2 inhibitor
|
SCH-479833 is a potent, specific and orally active CXCR1 and CXCR2 antagonist with Ki of 0.17 and 7 nM, respectively. |
| PC-20761 |
PF-07054894
CCR6 inhibitor
|
PF-07054894 is a potent, functionally selective CCR6 antagonist, blocks in vitro CCL20- dependent human T cell chemotaxis with IC50 of 5.7 nM. |
| PC-20733 |
AMG487
CXCR3 antagonist
|
AMG487 (AMG 487, VUF10085) is a potent and selective orally bioavailable chemokine (C-X-C motif) receptor 3 (CXCR3) antagonist with IC50 of 8 nM for inhibiting 125I-IP-10 binding. |
| PC-20530 |
INCB3284
CCR2 antagonist
|
INCB3284 (INCB 3284, INCB003284) is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM in antagonism of MCP-1 binding to hCCR2 and 4.7 nM in antagonism of chemotaxis activity. |
| PC-20372 |
IPG7236
CCR8 inhibitor
|
IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM. |
| PC-20291 |
NUCC-390 dihydrochloride
CXCR4 agonist
|
NUCC-390 dihydrochloride (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
| PC-20290 |
NUCC-390
CXCR4 agonist
|
NUCC-390 (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
| PC-20096 |
ACT-777991
CXCR3 inhibitor
|
ACT-777991 (ACT777991) is a highly potent and selective CXCR3 antagonist with IC50 of 33 nM. |
| PC-49866 |
RIST4721
CXCR2 inhibitor
|
RIST 4721 (Vimnerixin, AZD 4721) is a potent, specific and orally active antagonist of CXCR2, potently inhibits neutrophil chemotaxis with IC50 of 17 nM. |
| PC-49464 |
RPT193
CCR4 antagonist
|
RPT193 (Zelnecirnon, RPT-193) is a highly potent, selective and orally active CCR4 antagonist, inhibits CCL22- induces human Th2 chemotaxis with IC50 of 370 nM. |
