Chemical Structure : ACT-777991
CAS No.: 1967811-46-6
货号: PC-20096Not For Human Use, Lab Use Only.
ACT-777991 (ACT777991) is a highly potent and selective CXCR3 antagonist with IC50 of 33 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥2580 | In stock | |
5 mg | ¥4280 | In stock | |
10 mg | ¥7280 | In stock | |
25 mg | Get quote | ||
100 mg | Get quote |
大包装,大折扣!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ACT-777991 (ACT777991) is a highly potent and selective CXCR3 antagonist with IC50 of 33 nM.
ACT-777991 showed dose-dependent efficacy and target engagement in a mouse model of acute lung inflammation.
分子量 | 550.48 | |
分子式 | C20H20F6N8O2S | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(R)-1-(2-(2-hydroxyethyl)-4-(2-(trifluoromethyl)-4-(2-(trifluoromethyl)pyrimidin-5-yl)thiazol-5-yl)piperazin-1-yl)-2-(3-methyl-1H-1,2,4-triazol-1-yl)ethan-1-one |
1. Meyer EA, et al. J Med Chem. 2023 Mar 8. doi: 10.1021/acs.jmedchem.3c00074.
备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright