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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-CCR8 agonist 1
CCR8 agonist 1

Chemical Structure : CCR8 agonist 1

CAS No.:

CCR8 agonist 1

货号: PC-27092Not For Human Use, Lab Use Only.

CCR8 agonist 1 is a potent and selective CCR8 agonist with EC50 of 8 nM, shows no agonistic or antagonistic activity for CXCR2. CXCR4, CCR2 and CCR7.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CCR8 agonist 1 is a potent and selective CCR8 agonist with EC50 of 8 nM, shows no agonistic or antagonistic activity for CXCR2. CXCR4, CCR2 and CCR7.

物理化学性质&存储条件

分子量 474.54
分子式 C27H27FN4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl)-1-(3-(2-methoxyphenoxy)benzyl)piperidin-4-ol

参考文献

1. Li Q, et al. Eur J Med Chem. 2026 Jun 13;316:119064.

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