SB 265610 |CAS:211096-49-0 Probechem Biochemicals

Chemical Structure : SB 265610

CAS No.: 211096-49-0

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SB 265610 (SB265610;SB-265610)

货号: PC-60621Not For Human Use, Lab Use Only.

SB 265610 is a potent, selective, reversible CXCR2 antagonist with with Kd of 3.48 nM.

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10 mg	￥2280	In stock
25 mg	￥3680	In stock
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生物&药学活性

SB 265610 is a potent, selective, reversible CXCR2 antagonist with with Kd of 3.48 nM.
SB 265610 inhibits protein nitration induced by hyperoxia, reduces radical formation in hyperoxia-exposed newborn rat lung.
SB 265610 also induces G1 arrest, ans shows anti-proliferative activity in in IL8-rich tumor microenvironments.

物理化学性质&存储条件

分子量	357.16
分子式	C14H9BrN6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	100 mM in DMSO
Chemical Name/SMILES	N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea

参考文献

1. de Kruijf P, et al. J Pharmacol Exp Ther. 2009 May;329(2):783-90.

2. Bradley ME, et al. Br J Pharmacol. 2009 Sep;158(1):328-38.

3. de Kruijf P, et al. Mol Pharmacol. 2011 Dec;80(6):1108-18.

4. Goda AE, et al. Anticancer Res. 2015 Jun;35(6):3235-43.

SB 265610 (SB265610;SB-265610)

生物&药学活性

物理化学性质&存储条件

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SB 265610 (SB265610;SB-265610)

生物&药学活性

物理化学性质&存储条件

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