| Cat. No. |
Product Name |
Information |
| PC-42231 |
NSC632839
DUBs inhibitor
|
NSC632839 is a small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases, inhibits USP2, USP7, and SENP2 with EC50 values of 45 μM, 37 μM, and 9.8 μM, respectively. |
| PC-45498 |
LDN-57444
UCHL1 inhibitor
|
LDN57444 is a potent, reversible, competitive, active site-directed UCHL1 inhibitor with IC50 of 0.88 uM. |
| PC-45341 |
ML323
USP1 inhibitor
|
ML323 (ML 323) is a potent, selective, reversible inhibitor of the USP1/UAF1 deubiquitinase complex with IC50 of 76 nM. |
| PC-42288 |
ML364
USP2 inhibitor
|
ML364 is a potent, selective and reversible ubiquitin-specific protease USP2 inhibitor with IC50 of 1.1 uM. |
| PC-43555 |
P-50429
USP7/USP47 inhibitor
|
P-50429 (P50429, P 50429) is a potent, selective, covalent deubiquitinase USP7 (EC50=0.42 uM)/USP47 (EC50=1.0 uM) inhibitor with no inhibition for caspase 3, calpain 1, 20S proteasome and a panel of representative USPs. |
| PC-45339 |
HBX-19818
USP7 inhibitor
|
HBX-19818 is a potent, selective USP7 inhibitor with IC50 of 28.1 uM. |
| PC-45856 |
USP8-IN-22d
USP8 inhibitor
|
USP8-IN-22d is a potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM. |
| PC-45857 |
USP8-IN-22c
USP8 inhibitor
|
USP8-IN-22c is a potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM. |
| PC-45056 |
USP7-IN-1
USP7 inhibitor
|
USP7-IN-1 is a novel selective and reversible inhibitor of USP7 with IC50 of 33 uM. |
| PC-46007 |
SJB3-019A
USP1 inhibitor
|
SJB3-019A is a potent ubiquitin-specific protease USP1 inhibitor with IC50 of 78.1 nM, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells. |
| PC-23143 |
IsoLiPro
USP11 inhibitor
|
IsoLiPro is a novel small molecule USP11 inhibitor, reduces the USP11 protein level and suppressesthe USP11-mediated substrate deubiquitination. |
| PC-23140 |
LN-439A
BAP1 inhibitor
|
LN-439A is a small molecule BRCA1-associated protein 1 (BAP1) inhibitor by binding to the catalytic pocket of BAP1, leading to the ubiquitination and degradation of Krüppel-like factor 5 (KLF5), inhibits proliferation and migration of BLBC cells. |
