USP30 inhibitor Q14 peptide | USP30 inhibitor | Probechem Biochemicals

Chemical Structure : USP30 inhibitor Q14 peptide

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USP30 inhibitor Q14 peptide (USP30 inhibitor Q14)

货号: PC-72255Not For Human Use, Lab Use Only.

USP30 inhibitor Q14 peptide is a potent peptide inhibitor of USP30 with IC50 of 57.2 nM, inhibits the deubiquitinating activities of USP30, increases mitophagy.

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生物&药学活性

USP30 inhibitor Q14 peptide is a potent peptide inhibitor of USP30 with IC50 of 57.2 nM, inhibits the deubiquitinating activities of USP30, increases mitophagy.
Q14 peptide (18 aa) is derived from the transmembrane (TM) domain of USP30 that can target mitochondrial-anchored USP30 directly and increase mitophagy.
Q14 peptide inhibits the deubiquitinating activities of USP30 on both purified ubiquitin chains and ubiquitinated mitochondria.
Q14 peptide binds USP30 in vitro with Kd of 37 nM in fluorescence polarization (FP) assays.

物理化学性质&存储条件

分子量	2157.60
分子式	C99H165N31O23
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility
Chemical Name/SMILES	Sequence: Gly-Ile-Tyr-Val-Ile-Trp-Gly-Pro-Ile-Thr-Glu-Arg-Lys-Lys-Arg-Arg--Lys-Gly

参考文献

1. Xuan Qin, et al. Autophagy. 2022 Jan 6;1-20.

USP30 inhibitor Q14 peptide (USP30 inhibitor Q14)

生物&药学活性

物理化学性质&存储条件

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USP30 inhibitor Q14 peptide (USP30 inhibitor Q14)

生物&药学活性

物理化学性质&存储条件

参考文献

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