HBX-90659 (compound 22e, DUB-IN-2) | USP8 inhibitor | Probechem Biochemicals

Chemical Structure : HBX-90659

CAS No.: 924296-19-5

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HBX-90659 (HBX90659, compound 22e, USP8-IN-22e, DUB-IN-2)

货号: PC-72535Not For Human Use, Lab Use Only.

HBX-90659 (compound 22e, DUB-IN-2) is a potent, selective USP8 inhibitor with IC50 of 0.28 uM, with no effect on USP7 (IC50 of >100 uM).

规格	价格	库存
5 mg	￥1480	In stock
10 mg	￥2180	In stock
25 mg	￥3580	In stock
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100 mg		Get quote

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生物&药学活性

HBX-90659 (compound 22e, DUB-IN-2) is a potent, selective USP8 inhibitor with IC50 of 0.28 uM, with no effect on USP7 (IC50 of >100 uM).
HBX-90659 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 uM.

物理化学性质&存储条件

分子量	275.27
分子式	C15H9N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	9-(Ethoxyimino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile

参考文献

1. Matteo Colombo, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.

HBX-90659 (HBX90659, compound 22e, USP8-IN-22e, DUB-IN-2)

生物&药学活性

物理化学性质&存储条件

参考文献

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HBX-90659 (HBX90659, compound 22e, USP8-IN-22e, DUB-IN-2)

生物&药学活性

物理化学性质&存储条件

参考文献

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