| Cat. No. |
Product Name |
Information |
| PC-22864 |
USP1 inhibitor C527
USP1 inhibitor
|
USP1 inhibitor C527 is a specific small-molecule inhibitor of USP1 blocking the deubiquitinating enzyme activity of USP1 with IC50 of 0.88 uM (USP/UAF1 complex). |
| PC-22863 |
Zerumbone
TAGLN/USP1 inhibitor
|
Zerumbone is a natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet with anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity, binds to transgelin (TAGLN) and reduces the retention of USP1 in the cytoplasm and the degradation of ZEB1 ubiquitination. |
| PC-22320 |
Compound 7695-0983
FAT10 inhibitor
|
Compound 7695-0983 is a small molecule inhibitor of HLA-F locus-adjacent transcript 10 (FAT10), inhibits the expression of FAT10, inhibits NEDD4-PTEN/AKT axis-mediated autophagy. |
| PC-22319 |
IMP-2586
USP30 inhibitor
|
IMP-2586 is a potent, selective ubiquitin-specific protease 30 (USP30) inhibitor with IC50 of 16.3 nM, binding Ki of 5.6 nM. |
| PC-22318 |
IMP-2587
USP30 inhibitor
|
IMP-2587 is a potent, selective ubiquitin-specific protease 30 (USP30) inhibitor with IC50 of 12.6 nM, binding Ki of 42.7 nM. |
| PC-22183 |
Vialinin A
USP4/USP5 inhibitor
|
Vialinin A (Terrestrin A) is a p-terphenyl compound with antioxidant properties, inhibits the peptidase activity of USP5/IsoT with IC50 of 5.9 uM, also inhibits the enzymatic activities of USP4 with IC50 of 1.5 uM. |
| PC-21559 |
USP3 inhibitor 59
USP3 inhibitor
|
USP3 inhibitor 59 is a relatively specific small molecule chemical handle with SPR value of 14 uM, binds to zinc-finger ubiquitin binding domain (ZnF-UBD). |
| PC-20592 |
USP28 inhibitor 19
USP28 inhibitor
|
USP28 inhibitor 19 is a potent, selective USP28 inhibitor with IC50 of 1.1 uM, does not inhibit USP7 and LSD1 (IC50>100 uM). |
