| Cat. No. |
Product Name |
Information |
| PC-38800 |
JX-7
NNRTI
|
JX-7 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with remarkable inhibitory activity against wild-type HIV-1 (EC50=5 nM) and numerous clinically observed variants in MT-4 cells. |
| PC-38744 |
Emivirine
HIV-1 RT inhibitor
|
Emivirine (MKC-442) is a highly potent and selective inhibitor of HIV-1 reverse transcriptase (RT) with IC50 of 8 nM, does not inhibit HIV-1 RNase H, other RTs, or DNA polymerase alpha. |
| PC-38643 |
GSK3839919
HIV-1 integrase inhibitor
|
GSK3839919 is a potent, allosteric HIV-1 integrase inhibitor (ALLINI) with IC50 of 11.1 nM, exhibits broad-spectrum antiviral potency. |
| PC-38594 |
BRD-K98645985
BAF inhibitor
|
BRD-K98645985 is a small molecule inhibitor of BAF (mammalian SWI/SNF)-mediated transcription with EC5 of 2.37 uM, binds ARID1A-specific BAF complexes, reverses HIV-1 latency in vitro and ex vivo. |
| PC-38563 |
Temsavir
HIV-1 attachment inhibitor
|
Temsavir (BMS-626529) is a highly potent, small molecule HIV-1 attachment inhibitor with IC50 values of 2.26 nM, 0.34 nM and 1.3 nM for HIV-1 subtype A, B, and C envelope, repectively. |
| PC-38556 |
Q308
HIV-1 Tat inhibitor
|
Q308 is a small molecule that silences the latent HIV-1 provirus by inhibiting Tat-mediated gene transcription and selectively downregulates the expression levels of the facilitated chromatin transcription (FACT) complex. |
| PC-38555 |
ACAi-028
HIV-1 capsid inhibitor
|
ACAi-028 is a small molecule inhibiting HIV-1 replication (EC50=0.55 uM) that targets a hydrophobic pocket in the N-terminal domain of capsid (CA-NTD). |
| PC-38494 |
SRI-41897
HIV-1 Vpu inhibitor
|
SRI-41897 is a specific small molecule inhibitor of HIV-1 N-terminal region of NL4-3 Vpu (HIV-1 NL4-3 Vpu) with EC50 of 4.4 uM in the GaLV inhibition assays. |
| PC-38387 |
Elunonavir
HIV protease inhibitor
|
Elunonavir (GS-1156) is an azapeptide atazanavir analogs and HIV protease inhibitor, useful for treating HIV infections. |
| PC-73436 |
STP0404
HIV-1 integrase inhibitor
|
Pirmitegravir (STP0404) is a highly potent, first-in-class, allosteric HIV-1 integrase inhibitor (ALLINI) with IC50 of 0.41 nM against HIV-1NL4-3 in human PBMCs. |
| PC-73411 |
Claficapavir
HIV-1 inhibitor
|
Claficapavir (A1752) is a specific small molecule inhibitor of HIV-1 nucleocapsid protein (Kd=20 nM), shows a strong antiviral efficacy with IC50 of 1 uM. |
| PC-73248 |
FD028
HIV-1 inactivator
|
FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41. |
