| Cat. No. |
Product Name |
Information |
| PC-23159 |
Compound 484
HIV-1 inhibitor
|
Compound 484 is a small molecule inhibitor of HIV-1 envelope glycoprotein function that block two CD4-induced conformational changes, exhibits broad range activity against diverse HIV-1 strains. |
| PC-22959 |
HT-7
BST2 modulator
|
HT-7 is a specific, heterocyclic HIV-1 inhibitor inhibits viral release by inducing cell surface bone marrow stromal antigen 2 (BST2)/Tetherin/CD317/HM1.24, increases cell surface BST2 coupled with HIV-1 release reduction in Jurkat cells but not Jurkat/KO-BST2 cells. |
| PC-22715 |
Ainuovirine
NNRTI
|
Ainuovirine is a third-generation non-nucleoside reverse-transcriptase inhibitor (NNRTI) as anti-HIV-1 agent. |
| PC-22328 |
Bevirimat
HIV-1 maturation inhibitor
|
Bevirimat (PA-457) is a potent HIV inhibitor that inhibits HIV Gag protein processing and viral maturation. |
| PC-22327 |
JRC-II-191
CD4 mimic
|
JRC-II-191 is a small-molecule CD4 mimic with Kd of 760 nM for gp120 envelope glycoprotein, inhibits HIV-1 entry by blocking the binding of the HIV-1 envelope glycoprotein gp120 to the CD4 receptor. |
| PC-22321 |
Lamivudine
NRTI
|
Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI), inhibits HIV reverse transcriptase and also the reverse transcriptase of HBV, also inhibits long interspersed nuclear element-1 (LINE-1 or L1) reverse transcriptase. |
| PC-21968 |
Bavtavirine
NNRTI
|
Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) against HIV-1. |
| PC-21806 |
Cabotegravir
HIV-1 integrase inhibitor
|
Cabotegravir (GSK-1265744) is a potent, selective HIV-1 integrase inhibitor with IC50 of 3 nM in biochemical integrase strand transfer assay (INST). |
| PC-21700 |
Lopinavir
HIV-1 protease inhibitor
|
Lopinavir (ABT-378) is a highly potent inhibitor of HIV-1 protease with Ki of 1.3 to 3.6 pM for wild-type and mutant HIV protease. |
| PC-20513 |
BDM2
IN-LEDGF/p75 inhibitor
|
BDM2 is a potent, HIV-1 Integrase IN-LEDGF allosteric inhibitor (INLAI), shows potent anti-HIV activity. |
| PC-36158 |
HIV-1 inhibitor 5b
|
HIV-1 inhibitor 5b is a novel anti-HIV-1 compound that inhibits HIV-1 JR-CSF with EC50 of 1 nM without significant cytotoxicity (CC50>20 uM), also shows potency against NRTI- and NNRTI-resistant HIV-1 (EC50=1-3 nM). |
| PC-43418 |
Dolutegravir sodium
|
Dolutegravir sodium (GSK-1349572A) is a potent, next-generation HIV integrase (IN) inhibitor, inhibits HIV-1 integrase-catalyzed strand transfer with IC50 of 2.7 nM. |
