DPC-681 |CAS:284661-68-3 Probechem Biochemicals

Chemical Structure : DPC-681

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DPC-681 (DPH-153893, DPC681)

货号: PC-45631Not For Human Use, Lab Use Only.

DPC-681 (DPH-153893) is a potent and selective inhibitor of HIV-1 protease with IC90 of 4-40 nM.

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生物&药学活性

DPC-681 (DPH-153893) is a potent and selective inhibitor of HIV-1 protease with IC90 of 4-40 nM.
DPC-681 displays no loss in potency towardrecombinant mutant HIVs with the D30N mutation and a fivefold or smaller loss in potency toward mutant variants with three to five amino acid substitutions.

物理化学性质&存储条件

分子量	669.8495
分子式	C35H48FN5O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Valinamide, N-[(3-fluorophenyl)methyl]glycyl-N-[(1S,2R)-3-[[(3-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-3-methyl-

参考文献

1. Kaltenbach RF 3rd, et al. Antimicrob Agents Chemother. 2001 Nov;45(11):3021-8.

2. Solon EG, et al. Drug Metab Dispos. 2002 Nov;30(11):1164-9.

DPC-681 (DPH-153893, DPC681)

生物&药学活性

物理化学性质&存储条件

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DPC-681 (DPH-153893, DPC681)

生物&药学活性

物理化学性质&存储条件

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