Nevirapine |CAS:129618-40-2 Probechem Biochemicals

Chemical Structure : Nevirapine

CAS No.: 129618-40-2

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Nevirapine (BI-RG 587;NSC 641530;NVP)

货号: PC-42657Not For Human Use, Lab Use Only.

A potent and specific non-nucleoside inhibitor (NNRTI) of HIV-1 reverse transcriptase with Ki of 0.2 uM.

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50 mg	￥880	In stock
100 mg	￥1380	In stock
200 mg	￥2180	In stock
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生物&药学活性

Nevirapine (BI-RG 587, NSC 641530) is a potent and specific non-nucleoside inhibitor (NNRTI) of HIV-1 reverse transcriptase with Ki of 0.2 uM.
Nevirapine shows no effect on feline and simian RT or any mammalian DNA polymerases.
Nevirapine inhibits HIV-1 replication and protein p24 production.

物理化学性质&存储条件

分子量	266.2979
分子式	C15H14N4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-methyl-

参考文献

1. Merluzzi VJ, et al. Science. 1990 Dec 7;250(4986):1411-3.

2. Cohen KA, et al. J Biol Chem. 1991 Aug 5;266(22):14670-4.

3. Richman D, et al. Antimicrob Agents Chemother. 1991 Feb;35(2):305-8.

Nevirapine (BI-RG 587;NSC 641530;NVP)

生物&药学活性

物理化学性质&存储条件

参考文献

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Nevirapine (BI-RG 587;NSC 641530;NVP)

生物&药学活性

物理化学性质&存储条件

参考文献

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