Cat. No. |
Product Name |
Information |
PC-61517 |
NPD4456
HIV-1 Vpr inhibitor
|
NPD4456 is a coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages. |
PC-61452 |
BMS-955176
HIV-1 maturation inhibitor
|
BMS-955176 (GSK3532795) is a second-generation HIV-1 maturation inhibitor that exhibits potent activity (EC50=3.9±3.4 nM) against a library (n=87) of gag/pr recombinant viruses. |
PC-61409 |
MIV 150
NNRTI
|
MIV 150 (PC-815) is a high-affinity, allosteric HIV-1 and HIV-2 reverse transcriptase inhibitor (NNRTI) with EC50 of 1 nM. |
PC-61408 |
Carrageenan
HIV inhibitor
|
Carrageenan is a linear sulfated polysaccharide extracted from red edible seaweeds, shows topical microbicide activity targeting HIV viruses. |
PC-61259 |
Stilbenavir
HIV-1 inhibitor, Fap1 inhibitor
|
Stilbenavir (NSC34931) is an anti-HIV-1 compound that interferes with HIV-I integrase binding to viral DNA, also inhibits Fas-associated phosphatase 1 (Fap1). |
PC-70242 |
L-870810
HIV integrase inhibitor
|
A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties. |
PC-70236 |
SCH 350581
CCR5 inhibitor
|
SCH 350581 (AD-101) is a specific small molecule inhibitor of CCR5, inhibits HIV-1 entry. |
PC-70235 |
SCH 351125
HIV-1 entry inhibitor
|
SCH 351125 (Ancriviroc) is a small molecule inhibitor of HIV-1 entry via the CCR5 coreceptor. |
PC-70320 |
DMJ-I-228
gp120-CD4 inhibitor
|
DMJ-I-228 is a small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM. |
PC-70319 |
JP-III-48
gp120-CD4 inhibitor
|
JP-III-48 is a small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry. |
PC-70309 |
DDX3-IN-16d
DDX3 inhibitor
|
DDX3-IN-16d is a small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3), a human host factor required for the replication of several DNA and RNA viruses. |
PC-61164 |
BMS-986001
NRTI
|
A thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM. |