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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-DB213
DB213

Chemical Structure : DB213

CAS No.: 209163-39-3

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DB213 (RG-501)

货号: PC-62359Not For Human Use, Lab Use Only.

DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication, causes an imbalance in the ratio of Gag to Gag-Pol, and inhibits viral particle assembly.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication, causes an imbalance in the ratio of Gag to Gag-Pol, and inhibits viral particle assembly.

    物理化学性质&存储条件

    分子量 478.328
    分子式 C18H36Cl4N6
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N1,N4-bis(3-(dimethylamino)propyl)terephthalimidamide tetrahydrochloride

    参考文献

    1. Marcheschi RJ, et al. ACS Chem Biol. 2011 Aug 19;6(8):857-64.

    2. Hung M, et al. J Virol. 1998 Jun;72(6):4819-24.

    3. Wang Q, et al. J Pharm Biomed Anal. 2016 Jun 5;125:41-7.

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