| Cat. No. |
Product Name |
Information |
| PC-73247 |
S2C3
HIV entry inhibitor
|
S2C3 is a small molecule HIV-1 fusion inhibitor, targets the membrane proximal external region (MPER) of HIV-1 envelope spike. |
| PC-73246 |
NBD-14273
HIV entry inhibitor
|
NBD-14273 is a CD4-mimetic, small-molecule HIV-1 entry inhibitor with IC50 of 0.13 uM. |
| PC-72683 |
GSK3739936
HIV-1 integrase inhibitor
|
GSK3739936 (BMS-986180) is a potent, allosteric HIV-1 integrase (ALLINI), shows excellent potency in vitro against majority of the 124/125 variants (EC50=1.7 nM). |
| PC-72633 |
HIV-1 Integrase inhibitor GS-B
HIV-1 integrase inhibitor
|
HIV-1 Integrase inhibitor GS-B (GS-B) is a novel non-catalytic site integrase inhibitor of HIV-1 integrase (IN), inhibits the interaction between LEDGF IBD and IN with IC50 of 8.1 nM. |
| PC-72632 |
JTP-0157602
HIV-1 integrase inhibitor
|
JTP-0157602 (JTP0157602) is a novel non-catalytic site integrase inhibitor of HIV-1 integrase (IN), inhibits the interaction between LEDGF IBD and IN with IC50 of 4.2 nM. |
| PC-72614 |
NBD-14270
HIV-1 gp120 inhibitor
|
NBD-14270 (NBD14270) is an HIV-1 gp120 antagonist, shows antiviral activity against HIV-1HXB2 with IC50 of 180 nM. |
| PC-72601 |
GSK3640254
HIV-1 maturation inhibitor
|
GSK3640254 (GSK254, Fipravirimat) is a novel potent HIV-1 maturation inhibitor with EC90 of 33 nM against a minilibrary of clinically relevant HIV-1 polymorphisms in a multiple-cycle assay. |
| PC-72432 |
SBI-0637142
Latency-reversing agent
|
SBI-0637142 is a potent Smac mimetic that preferentially targets BIRC2, latency-reversing agent (LRA), specifically and potently promote HIV-1 latency reversal activity. |
| PC-72431 |
Ciapavir
Latency-reversing agent
|
Ciapavir (SBI-0953294, cIAP1 antagonist for viral reactivation) is a bivalent, next-generation, Smac mimetic and antagonist of cIAP1 as latency-reversing agent (LRA), specifically and potently promote HIV-1 latency reversal activity both in vivo. |
| PC-38204 |
FC-8052
HIV-1 Nef inhibitor
|
FC-8052 (FC8052) is a highly potent inhibitor of HIV-1 Nef-effector kinase, binds to recombinant Nef in vitro with Kd of 10 pM. |
| PC-38203 |
SRI-37264
HIV-1 Nef inhibitor
|
SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation. |
| PC-36113 |
ZBMA-1
HIV-1 Vif inhibitor
|
ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex. |
