FD028 | HIV-1 inactivator | Probechem Biochemicals

Chemical Structure : FD028

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FD028 (FD-028, FD 028)

货号: PC-73248Not For Human Use, Lab Use Only.

FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41.
FD028 is not significantly toxic and has broad-spectrum HIV-1 inhibitory and inactivation activity, including T20-resistant viruses and T2635-resistant viruses.

物理化学性质&存储条件

分子量	881.812
分子式	C42H39Cl2FN4O8S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-2-chloro-5-(5-((3-(4-(2-(4-(2-((4-chloro-3-fluorophenyl)amino)-2-oxoacetamido)-2,2,6,6-tetramethylpiperidin-1-yl)-2-oxoethoxy)phenethyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid

参考文献

1. Jing Pu, et al. Front Pharmacol. 2021 Jan 25;11:613361. doi: 10.3389/fphar.2020.613361.

FD028 (FD-028, FD 028)

生物&药学活性

物理化学性质&存储条件

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FD028 (FD-028, FD 028)

生物&药学活性

物理化学性质&存储条件

参考文献

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