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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-GSK3739936
GSK3739936

Chemical Structure : GSK3739936

CAS No.: 1803444-21-4

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GSK3739936 (BMS-986180, GSK-3739936, BMS986180)

货号: PC-72683Not For Human Use, Lab Use Only.

GSK3739936 (BMS-986180) is a potent, allosteric HIV-1 integrase (ALLINI), shows excellent potency in vitro against majority of the 124/125 variants (EC50=1.7 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GSK3739936 (BMS-986180) is a potent, allosteric HIV-1 integrase (ALLINI), shows excellent potency in vitro against majority of the 124/125 variants (EC50=1.7 nM).

    物理化学性质&存储条件

    分子量 562.726
    分子式 C34H43FN2O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-2-(tert-butoxy)-2-(4-(4,4-dimethylpiperidin-1-yl)-5-(4-(4-fluorophenethoxy)phenyl)-2,6-dimethylpyridin-3-yl)acetic acid

    参考文献

    1. Naidu BN, et al. J Med Chem. 2022 Mar 24;65(6):4949-4971.

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