Rilpivirine |CAS:500287-72-9 Probechem Biochemicals

Chemical Structure : Rilpivirine

CAS No.: 500287-72-9

加入收藏

Rilpivirine (R 278474;TMC 278;R-278474;R278474;TMC278;TMC-278)

货号: PC-42661Not For Human Use, Lab Use Only.

Rilpivirine (R278474, TMC278) is a highly potent nonnucleoside inhibitor (NNRTI) of HIV-1 reverse trK7912:M7912anscriptase with IC50 of 0.4 nM for WT HIV-1 in cell-based assay.

规格	价格	库存
10 mg	￥780	In stock
25 mg	￥1180	In stock
50 mg	￥1880	In stock
100 mg	￥2980	In stock
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Rilpivirine (R278474, TMC278) is a highly potent nonnucleoside inhibitor (NNRTI) of HIV-1 reverse trK7912:M7912anscriptase with IC50 of 0.4 nM for WT HIV-1 in cell-based assay.
Rilpivirine (R278474, TMC278) shows activity against a panel of single and double HIV-1 site-directed mutant (IC50=0.3-2 nM); orally active.

物理化学性质&存储条件

分子量	366.4185
分子式	C22H18N6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzonitrile, 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]-

参考文献

1. Janssen PA, et al. J Med Chem. 2005 Mar 24;48(6):1901-9.

2. Das K, et al. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1466-71.

3. Azijn H, et al. Antimicrob Agents Chemother. 2010 Feb;54(2):718-27.

Rilpivirine (R 278474;TMC 278;R-278474;R278474;TMC278;TMC-278)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Rilpivirine (R 278474;TMC 278;R-278474;R278474;TMC278;TMC-278)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.