Chemical Structure : RO-0335
CAS No.: 867365-76-2
货号: PC-49139Not For Human Use, Lab Use Only.
RO-0335 is a highly potent, selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with IC50 of 8.1 nM, potently inhibits HIV replication with IC50 of 1.3 nM in cell based assays.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥1980 | In stock | |
25 mg | ¥3480 | In stock | |
50 mg | ¥5480 | In stock | |
100 mg | Get quote | ||
1 g | Get quote |
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RO-0335 is a highly potent, selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with IC50 of 8.1 nM, potently inhibits HIV replication with IC50 of 1.3 nM in cell based assays.
RO-0335 shows potent inhibition of Wt HIV-1 with IC50 of 1.1 nM and retains activity (protein shifted IC50 < 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
分子量 | 573.214 | |
分子式 | C21H13BrCl2FN3O4S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide |
1. H Javanbakht, et al. Antiviral Res. 2010 May;86(2):212-9.
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