SO-7g | NNRTI | Probechem Biochemicals

Chemical Structure : SO-7g

加入收藏

SO-7g (NNRTI SO-7g)

货号: PC-38861Not For Human Use, Lab Use Only.

SO-7g is a novel highly active HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI), exhibits moderate to excellent potency against wild-type HIV-1 with EC50 of 5.3 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SO-7g is a novel highly active HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI), exhibits moderate to excellent potency against wild-type HIV-1 with EC50 of 5.3 nM.
SO-7g displayed 30- and 16-fold improvement than nevirapine and zidovudine and comparable potency to efavirenz and etravirine.
SO-7g showed promising activity against a variety of mutant strains, especially for L100I (EC50= 0.047 μM), K103 N (EC50= 0.056 μM), and E138K (EC50= 0.040 μM).
SO-7g also exhibited low cytotoxicity (CC50= 65.63 μM) and high selectivity index (SI= 12392).

物理化学性质&存储条件

分子量	569.077
分子式	C27H29ClN6O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(2-((4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-2-azaspiro[3.3]heptan-6-yl)-1H-indole-2-carboxamide

参考文献

1. Shenghua Gao, et al. Eur J Med Chem. 2022 May 20;238:114471.

SO-7g (NNRTI SO-7g)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SO-7g (NNRTI SO-7g)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.