JX-7 | NNRTI | Probechem Biochemicals

Chemical Structure : JX-7

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JX-7 (NNRTI inhibitor)

货号: PC-38800Not For Human Use, Lab Use Only.

JX-7 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with remarkable inhibitory activity against wild-type HIV-1 (EC50=5 nM) and numerous clinically observed variants in MT-4 cells.

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生物&药学活性

JX-7 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with remarkable inhibitory activity against wild-type HIV-1 (EC50=5 nM) and numerous clinically observed variants in MT-4 cells.

物理化学性质&存储条件

分子量	438.447
分子式	C24H18N6O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-((6-amino-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-5,7-dimethoxy-2-naphthonitrile

参考文献

1. Xin Jin, et al. J Med Chem. 2022 Jun 1. doi: 10.1021/acs.jmedchem.2c00468.

JX-7 (NNRTI inhibitor)

生物&药学活性

物理化学性质&存储条件

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JX-7 (NNRTI inhibitor)

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物理化学性质&存储条件

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