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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-VTD227
VTD227

Chemical Structure : VTD227

CAS No.: 330858-64-5

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VTD227 (VTD-227, VTD 227)

货号: PC-47033Not For Human Use, Lab Use Only.

VTD227 is a small molecule Vpr-targeting HIV-1 inhibitor, directly binds to Vpr with Kd of 8.8 uM, inhibits HIV-1 replication in monocyte-derived macrophages (MDM) with IC50 of 0.78 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VTD227 is a small molecule Vpr-targeting HIV-1 inhibitor, directly binds to Vpr with Kd of 8.8 uM, inhibits HIV-1 replication in monocyte-derived macrophages (MDM) with IC50 of 0.78 uM.

    物理化学性质&存储条件

    分子量 329.356
    分子式 C17H19N3O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-2-(2-((2-hydroxynaphthalen-1-yl)methylene)hydrazinyl)-N-(3-methoxypropyl)-2-oxoacetamide

    参考文献

    1. Hirotaka Sato, et al. Viruses. 2022 Jun 16;14(6):1321.

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