| Cat. No. |
Product Name |
Information |
| PC-38278 |
KB-0742
CDK9 inhibitor
|
KB-0742 (KB0742) is a potent, orally bioavailable, selective CDK9 inhibitor with IC50 of 6 nM (CDK9/cyclin T1 inhibition). |
| PC-38149 |
A-1592668
CDK9 inhibitor
|
A-1592668 (A 1592668) is a novel potent, CDK9-selective inhibitor with IC50 of 1.2 nM, >1000 fold selectivity over CDK1/2/7/8. |
| PC-38063 |
bio-THZ1
CDK7 inhibitor
|
bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7.. |
| PC-36163 |
FMF-04-159-2
CDK14 inhibitor
|
FMF-04-159-2 is a potent, selective, covalent CDK14 inhibitor (IC50=86 nM) with pan-TAIRE family specificity (CDKs 14-18). |
| PC-36145 |
YKL-5-124
CDK7 inhibitor
|
YKL-5-124 is a novel potent, selective, and covalent CDK7 inhibitor (IC50=53.5 nM), inhibits CDK7/CycH/MAT1 enzymatic activity with IC50 of 9.7 nM. |
| PC-35969 |
PF-06873600
CDK2/4/6 inhibitor
|
PF-06873600 (Ebvaciclib, PF06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively. |
| PC-35809 |
CDK9 inhibitor HH1
CDK9 inhibitor
|
CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor. |
| PC-35808 |
MC180295
CDK9 inhibitor
|
MC180295 (MC-180295, MC 180295) is a novel potent, highly selective CDK9 inhibitor with IC50 of 5 nM, displays >22-fold selectivity over other CDKs. |
| PC-35787 |
LY3143921
Cdc7 inhibitor
|
LY3143921 (LY-3143921) is an orally available, potent, selective inhibitor of Cdc7 kinase inhibitor, inhibits CDC7/DBF4 I and pMCM2 (S53) with IC50 values of 3.3 nM and 290 nM, respectively.. |
| PC-35688 |
JSH-150
CDK9 inhibitor
|
JSH-150 (JSH150) is a potent, highly selective inhibitor of CDK9 kinase with IC50 of 1 nM in the biochemical assays, displays 300-10000-fold selectivity over other CDK kinase family members (CDK7 IC50=1.72 uM). |
| PC-35631 |
iCDK9
CDK9 inhibitor
|
iCDK9 (i-CDK9) is a potent, highly selective CDK9 inhibitor (IC50<0.4 nM, CDK9-CycT1 kinase), exhibits >600-fold selectivity toward CDK1-CycB, CDK2-CycA, CDK4-CycD1, CDK7-CycH-MAT1 and CDK8-CycC. |
| PC-35630 |
Amt-87
|
Amt-87 is a HIV latency-reversal agent that reactivates latent HIV at the transcriptional level, promotes phosphorylation of CDK9 T-loop at Thr186. |
