Cyclin-dependent Kinase (CDK) compound (inhibitors, antagonists)-ProbeChem.com

Request The Product List ofCyclin-dependent Kinase (CDK) Cyclin-dependent Kinase (CDK)

Cat. No.	Product Name	Information
PC-21703	CP681301 CDK5 inhibitor	CP681301 is a potent, highly specific CDK5 inhibitor, completely inhibits both CDK5-P35 and CDK5-P25 at 1 uM.
PC-21681	XPW1 CDK9 inhibitor	XPW1 is a potent and selective CDK9 inhibitor with excellent anti-ccRCC activity and low toxicity.
PC-21527	TMX-2039 pan CDK inhibitor	TMX-2039 is a pan-CDK inhibitor with low nanomolar enzymatic IC50s (0.5-50 nM) for both cell cycle CDKs (CDK1, CDK2, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9).
PC-20887	CDK2 inhibitor 5 CDK2 inhibitor	CDK2 inhibitor 5 is a potent, selective and allosteric CDK2 inhibitor with KD value of 18 nM, shows exquisite selectivity for CDK2 over CDK1.
PC-20691	NCGC00131308 IQGAP1-Cdc42 inhibitor	NCGC00131308 is a small molecule inhibitor that effectively disrupts IQGAP1-Cdc42 interaction in breast cancer cells, shows EC50 of 4.47 uM in biochemical HTRF assays.
PC-49786	MER-128 CDK20 inhibitor	MER-128 is a potent, selective CDK20 inhibitor with IC50 of 2 nM.
PC-49698	EF-4-177 CDK2 inhibitor	EF-4-177 is a potent, selective, allosteric and orally active CDK2 inhibitor with ITC KD of 7.4 nM. EF-4-177 binds CDK2 in a manner that is negatively cooperative with cyclin binding.
PC-38600	GSK-3/CDK5/CDK2-IN-1 GSK-3/CDK5/CDK2 inhibitor	GSK-3/CDK5/CDK2-IN-1 is an inhibitor of CDK5, CDK2 and GSK-3, inhibits the phosphorylation of Cdk5 peptide substrate phosphorylation with IC50 of <50 uM.

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