| Cat. No. |
Product Name |
Information |
| PC-60716 |
(±)-U-50488 hydrochloride
KOR antagonist
|
(±)-U-50488 hydrochloride is a potent, selective kappa-opioid receptor agonist with no μ-opioid antagonist effects. |
| PC-60715 |
(-)-U-50488 hydrochloride
KOR agonist
|
(-)-U-50488 hydrochloride is the more active enantiomer of (±)-U-50488, a potent, selective kappa-opioid receptor agonist (Kd=2.2 nM) with no μ-opioid antagonist effects. |
| PC-45977 |
Alvimopan dihydrate
μ-opioid receptor antagonist
|
Alvimopan (ADL 8-2698, LY246736) dihydrate selective peripherally acting μ-opioid antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus. |
| PC-45976 |
Alvimopan monohydrate
MOR antagonist
|
Alvimopan monohydrate (ADL 8-2698, LY 246736) is a selective peripherally acting μ-opioid (MOR) antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus. |
| PC-43423 |
Alvimopan
MOR antagonist
|
Alvimopan (LY 246736) is a selective peripherally acting μ-opioid (MOR) antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus. |
| PC-45979 |
Naltrexone
Opioid receptor antagonist
|
Naltrexone is a potent, competitive antagonist for μ, κ, δ, and σ-opioid receptors with Ki of 0.0825 nM, 0.509 nM, and 8.02 nM, for MOR, KOR, and DOR, respectively. |
| PC-45285 |
Meptazinol
MOR agonist
|
Meptazinol (IL-22811, WY-22811) is a partial µ-opioid receptor (MOR) agonist. |
| PC-42615 |
JDTic dihydrochloride
KOR antagonist
|
JDTic dihydrochloride is a highly potent and selective kappa Opioid receptor (KOR) antagonist with Ki of 0.3 nM. |
| PC-42614 |
JDTic
KOR antagonist
|
JDTic is a highly potent and selective kappa opioid receptor (KOR) antagonist with Ki of 0.3 nM. |
| PC-24299 |
Triazole 1.1
KOR agonist
|
Triazole 1.1 is a potent, G protein signaling-biased κ opioid receptor (KOR) agonist with EC50 of 77.2 nM in [35S]GTPγS binding assays, with bias factor (G protein/βarrestin2) of 28. |
| PC-24153 |
[D-Arg2] Dermorphin (1-4) acetate
MOR agonist
|
[D-Arg2] Dermorphin (1-4) acetate (Lumekefamide) is a potent, selective tetrapeptide μ-opioid receptor (μOR, MOR) agonist, shows antinociceptive effects. |
| PC-24152 |
[D-Arg2] Dermorphin (1-4)
MOR agonist
|
[D-Arg2] Dermorphin (1-4) (Lumekefamide) is a potent, selective tetrapeptide μ-opioid receptor (μOR, MOR) agonist, shows antinociceptive effects. |
