| Cat. No. |
Product Name |
Information |
| PC-61545 |
J-113397
NOP antagonist
|
J-113397 is a potent, selective nociceptin/orphanin FQ receptor (NOP receptor/ORL1) antagonist with IC50 of 2.3 nM. |
| PC-61544 |
Ro 64-6198
NOP agonist
|
Ro 64-6198 is a nonpeptidic, selective, brain-penetrant agonist of nociceptin/orphanin FQ receptor (NOP receptor/ORL1) with pKi of 9.41. |
| PC-61543 |
Ro 64-6198 hydrochloride
ORL1 agonist
|
Ro 64-6198 hydrochloride is a nonpeptidic, selective, brain-penetrant agonist of nociceptin/orphanin FQ receptor (NOP receptor/ORL1) with pKi of 9.41. |
| PC-61542 |
MT-7716
ORL1 agonist
|
A highly potent, brain-penetrating ORL1 receptor (NOP receptor) agonist with Ki of 0.76 and 0.50 nM for rat and human ORL1 receptors, respectively. |
| PC-61541 |
W-212393
ORL1 agonist
|
W-212393 (MT-7716 free base) is a highly potent, brain penetrant ORL1 receptor (NOP receptor) agonist with Ki of 0.76 and 0.50 nM for rat and human ORL1 receptors, respectively. |
| PC-61540 |
SR-16835
NOP receptor agonist
|
SR-16835 is a potent full agonist of ORL1 receptor (NOP receptor) with binding Ki of 11.4 nM, with low-affinity mu-opioid partial agonist activity (Ki=79.9 nM). |
| PC-61539 |
SR-16507
ORL1 agonist
|
SR-16507 is a potent full agonist of ORL1 receptor (NOP receptor) and partial agonist of mu-opioid receptor with Ki of 5.22 nM and 1.07 nM, respectively. |
| PC-61538 |
SR-16430
ORL1 inhibitor
|
SR-16430 is a selective ORL1 receptor (NOP receptor) antagonist that has 10-fold selectivity over μ-opioid receptor. |
| PC-61537 |
SR-14150
NOP/MOR agonist
|
SR-14150 is a potent NOP/μ-opioid partial agonist with Ki of 1.39 nM and 29.9 nM, respectively. |
| PC-61536 |
SR16435
NOP/MOR agonist
|
SR16435 is a mixed NOP/μ-opioid partial agonist with equally high affinity (Ki=29 nM) for both NOP and μ-opioid receptors. |
| PC-70351 |
TAN-67 dihydrobromide
δ-opioid receptor agonist
|
TAN-67 dihydrobromide (SB205607) is a potent and selective δ-opioid receptor agonist that has high affinity and selectivity for the δ1 subtype with Ki of 1.12 nM. |
| PC-70350 |
KNT-127
DOR agonist
|
KNT-127 is a potent, selective δ-opioid receptor (DOR) agonist with Ki of 0.16 nM, dispalys 133.5-fold and 960.5-fold selectivity over μOR and κOR respectively. |
