欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-AT-090
AT-090

Chemical Structure : AT-090

CAS No.: 2099681-59-9

加入收藏

AT-090 (AT090, AT 090)

货号: PC-61549Not For Human Use, Lab Use Only.

AT-090 is a potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 5.61 nM.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AT-090 is a potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 5.61 nM.
    AT-090 displays >15-fold selectivity over mu, and >40-fold over kappa opioid receptors.
    AT-090 induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ.
    AT-090 is a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists.

    物理化学性质&存储条件

    分子量 354.494
    分子式 C22H30N2O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-(1-((1s,4s)-4-iso-propylcyclohexyl)piperidin-4-yl)indoline-2,3-dione

    参考文献

    1. Ferrari F, et al. Eur J Pharmacol. 2016 Dec 15;793:1-13.

    2. Asth L, et al. Neuropharmacology. 2016 Jun;105:434-442.

    备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: