| Cat. No. |
Product Name |
Information |
| PC-62108 |
PF-04455242
KOR antagonist
|
PF-04455242 is a potent, selective κ-opioid receptor (KOR) antagonist with Ki of 3 nM/21 nM/22 nM for hKOR/rKOR/mKOR, respectively. |
| PC-62107 |
Enadoline
KOR agonist
|
Enadoline (CI 977, PD 129290) is a potent, selective κ-opioid receptor (KOR) agonist with Ki of 0.11 nM, binding with high affinity to [3H]-U69593-labelled kappa-sites. |
| PC-61887 |
Spiradoline mesylate
KOR agonist
|
Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects.. |
| PC-61886 |
Spiradoline
KOR agonist
|
Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects. |
| PC-61682 |
Oliceridine hydrochloride
MOR agonist
|
Oliceridine hydrochloride (Olinvo, TRV130) is a potent, selective, and G protein biased μ opioid receptor (MOR) agonist with pEC50 of 8.1. |
| PC-61681 |
Oliceridine
MOR agonist
|
Oliceridine (Olinvo, TRV130) is a potent, selective, and G protein biased μ opioid receptor (MOR) agonist with pEC50 of 8.1. |
| PC-61596 |
SR-8993
NOP-R agonist
|
SR-8993 is a potent, highly selective, brain-penetrant NOP-R (Nociceptin/orphanin FQ receptor) agonist with EC50 of 8.8 nM. |
| PC-61588 |
MK-1925
ORL1 agonist
|
MK-1925 is a selective, orally active, brain-penetrant opioid receptor-like 1 (ORL1. |
| PC-61550 |
AT-127
NOP receptor agonist
|
AT-127 is a potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 1.18 nM. |
| PC-61549 |
AT-090
NOP receptor agonist
|
AT-090 is a potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 5.61 nM. |
| PC-61547 |
SB-612111
NOP receptor antagonist
|
SB-612111 is a potent, selective nociceptin/orphanin FQ receptor (NOP receptor) antagonist with Ki of 0.33 nM. |
| PC-61546 |
LY2940094
NOP receptor antagonist
|
LY2940094 (BTRX246040) is a potent, selective, CNS-penetrant, orally available NOP (Nociceptin/OFQ) receptor antagonist with Kb of 0.17 nM. |
