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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-CYM51010
CYM51010

Chemical Structure : CYM51010

CAS No.: 1069498-96-9

CYM51010 (CID23723457, OPRM1-OPRD1 agonist ML335)

货号: PC-62146Not For Human Use, Lab Use Only.

CYM51010 (ML335) is an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerization with EC50 of 403 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CYM51010 (ML335) is an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerization with EC50 of 403 nM.
ML335 displays 37, 2.7, and >99-fold selectivity over OPRM1, OPRD1, and HTR5A, respectively.

物理化学性质&存储条件

分子量 408.542
分子式 C25H32N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[[4-(acetylamino)phenyl]methyl]-4-(2-phenylethyl)-4-piperidinecarboxylic acid, ethyl ester

参考文献

1. Pinello C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

2. Lolicato M, et al. Nature. 2017 Jul 10. doi: 10.1038/nature22988.

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