Eluxadoline |CAS:864821-90-9 Probechem Biochemicals

Chemical Structure : Eluxadoline

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Eluxadoline (JNJ-27018966; JNJ27018966)

货号: PC-60737Not For Human Use, Lab Use Only.

A potent, selective, orally bioavailable µ-opioid receptor agonist and a δ-opioid receptor antagonist for the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D)..

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25 mg		Get quote
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1 g		Get quote

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生物&药学活性

Eluxadoline (JNJ27018966) is a potent, selective, orally bioavailable µ-opioid receptor agonist and a δ-opioid receptor antagonist for the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D).

物理化学性质&存储条件

分子量	569.651
分子式	C32H35N5O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(((S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoic acid

参考文献

1. Dove LS, et al. Gastroenterology. 2013 Aug;145(2):329-38.e1.

2. Fujita W, et al. Biochem Pharmacol. 2014 Dec 1;92(3):448-56.

3. Davenport JM, et al. J Clin Pharmacol. 2015 May;55(5):534-42.

Eluxadoline (JNJ-27018966; JNJ27018966)

生物&药学活性

物理化学性质&存储条件

参考文献

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Eluxadoline (JNJ-27018966; JNJ27018966)

生物&药学活性

物理化学性质&存储条件

参考文献

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