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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-TRV0109101 hydrochloride
TRV0109101 hydrochloride

Chemical Structure : TRV0109101 hydrochloride

CAS No.: 2101210-22-2

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TRV0109101 hydrochloride ((R)-TRV0109101 hydrochloride, TRV 0109101 hydrochloride)

货号: PC-60803Not For Human Use, Lab Use Only.

TRV0109101 hydrochloride is a selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TRV0109101 hydrochloride is a selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.

    物理化学性质&存储条件

    分子量 392.986
    分子式 C21H29ClN2OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (R)-2-(9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)-N-(thiophen-2-ylmethyl)ethan-1-amine hydrochloride

    参考文献

    1. Koblish M, et al. J Pharmacol Exp Ther. 2017 Aug;362(2):254-262.

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