SNC80 (NIH-10815) | δ-opioid receptor agonist | Probechem Biochemicals

Chemical Structure : SNC80

CAS No.: 156727-74-1

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SNC80 (NIH-10815, SN-C80)

货号: PC-70349Not For Human Use, Lab Use Only.

SNC80 (NIH-10815) is a highly selective, non-peptide agonist of the δ-opioid receptor (δ-OR) with IC50/Ki of 2.73/0.18 nM.

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5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥4280	In stock
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100 mg		Get quote

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生物&药学活性

SNC80 (NIH-10815) is a highly selective, non-peptide agonist of the δ-opioid receptor (δ-OR) with IC50/Ki of 2.73/0.18 nM.
SNC80 displays >2,000-fold selectivity over the μ-opioid receptor.
SNC80 selectively activates μ-δ heteromers to produce maximal antinociception.

物理化学性质&存储条件

分子量	449.6
分子式	C28H39N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-benzamide

参考文献

1. Calderon SN, et al. J Med Chem. 1994 Jul 8;37(14):2125-8.

2. Bilsky EJ, et al. J Pharmacol Exp Ther. 1995 Apr;273(1):359-66.

3. Metcalf MD, et al. ACS Chem Neurosci. 2012 Jul 18;3(7):505-9.

SNC80 (NIH-10815, SN-C80)

生物&药学活性

物理化学性质&存储条件

参考文献

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SNC80 (NIH-10815, SN-C80)

生物&药学活性

物理化学性质&存储条件

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