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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-TAN-67 dihydrobromide
TAN-67 dihydrobromide

Chemical Structure : TAN-67 dihydrobromide

CAS No.: 1217628-73-3

TAN-67 dihydrobromide (SB205607 dihydrobromide)

货号: PC-70351Not For Human Use, Lab Use Only.

TAN-67 dihydrobromide (SB205607) is a potent and selective δ-opioid receptor agonist that has high affinity and selectivity for the δ1 subtype with Ki of 1.12 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TAN-67 dihydrobromide (SB205607) is a potent and selective δ-opioid receptor agonist that has high affinity and selectivity for the δ1 subtype with Ki of 1.12 nM.
TAN-67 dispalys >1,000-fold selectivity over μOR and κOR.

物理化学性质&存储条件

分子量 506.28
分子式 C23H24N2O.2HBr
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((4aS,12aR)-2-methyl-1,3,4,5,12,12a-hexahydropyrido[3,4-b]acridin-4a(2H)-yl)phenol dihydrobromide

参考文献

1. Knapp RJ, et al. Eur J Pharmacol. 1995 Oct 15;291(2):129-34.

2. Tseng LF, et al. J Pharmacol Exp Ther. 1997 Feb;280(2):600-5.

3. Fusa K, et al. Neuroscience. 2005;130(3):745-55.

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