| Cat. No. |
Product Name |
Information |
| PC-24736 |
WMJ-J-09
HDAC inhibitor
|
WMJ-J-09 is a potent, hydroxamate based HDAC inhibitor, exhibits potent inhibitory activity against class I HDACs, including HDAC1 (IC50=7.5 nM), HDAC2 (IC50=21.3 nM), HDAC3 (IC50=18.4 nM), and HDAC8 (IC50=90.9 nM), also strongly inhibitsHDAC6 (class IIb) with IC50 of 3.9 nM. |
| PC-24619 |
Bisthianostat
HDAC inhibitor
|
Bisthianostat (CF367) is an orally bioavailable pan-inhibitor of human histone deacetylase (HDAC) with IC50 of 0.07, 0.26 and 0.79 uM for HDAC1, HDAC2 and HDAC6 respectively. |
| PC-24323 |
Trichostatin A
HDAC inhibitor
|
Trichostatin A (TSA) is a potent and specific, irreversible inhibitor of class I/II HDACs with IC50 of 1.8 nM for HDAC. |
| PC-24022 |
HDAC11 inhibitor B6
HDAC11 inhibitor
|
HDAC11 inhibitor B6 is a potent, highly selective HDAC11 inhibitor with IC50 of 51.1 nM, >90-fold selective over HDAC8 and shows no activity against all other HDAC subtypes. |
| PC-23992 |
DS-103
HDAC inhibitor
|
DS-103 is a potent HDAC inhibitor with IC50 of 29/123/23/367 nM for HDAC1/2/3/6, weakly inhibits HDAC8 and no activity against class IIa member HDAC4. |
| PC-23965 |
HDAC3 inhibitor LSQ-28
HDAC3 inhibitor
|
LSQ-28 is a potent, selective HDAC3 inhibitor with IC50 of 42 nM, >150-fold selective over HDAC1, HDAC2, and HDAC6. |
| PC-23420 |
4-phenylbutyric acid
HDAC inhibitor
|
4-phenylbutyric acid (4-PBA) is a specific endoplasmic reticulum (ER) stress inhibitor, inhibits HDAC activity and increases histone acetylation levels. |
| PC-22801 |
HDAC6 inhibitor 5a
HDAC6 inhibitor
|
HDAC6 inhibitor 5a (MPI_5a, MPI-5a) is a potent and selective HDAC6 inhibitor with IC50 of 36 nM, >50-fold selectivity over other HDACs. |
| PC-22791 |
Givinostat
HDAC inhibitor
|
Givinostat (ITF-2357) is a potent, orally active, pan-HDAC inhibitor with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. |
| PC-22427 |
PCI-34051
HDAC8 inhibitor
|
PCI-34051 is a potent, specific HDAC8 inhibitor with IC50 of 10 nM, >200-fold selectivity over other HDAC isoforms. |
| PC-21844 |
RBC1HI
HDAC1/2 inhibitor
|
RBC1HI (Regenacy Brain Class I HDAC Inhibitor) is a novel specific small molecule HDAC1/HDAC2 inhibitor, attenuates behavioral manifestations of oxycodone withdrawal, especially in mice with neuropathic pain. |
| PC-21537 |
HR488B
HDAC1 inhibitor
|
HR488B is a potent, selective HDAC1 inhibitor with IC50 of 1.24 uM, effectively inhibits the proliferation of CRC cells. |
