| Cat. No. |
Product Name |
Information |
| PC-27053 |
HDAC6 inhibitor 4e
HDAC6 inhibitor
|
HDAC6 inhibitor 4e is a potent, isoform-selective HDAC6 inhibitor with IC50 of 1.7 nM, shows 355-fold selectivity over HDAC1. |
| PC-27052 |
HDAC6 inhibitor Compound 7b
HDAC6 inhibitor
|
HDAC6 inhibitor Compound 7b is a potent, selective HDAC6 inhibitor, inhibits proliferation, colony and spheroid formation as well as viability of prostate cancer cells, kills prostate cancer cells via HSP90α hyperacetylation-mediated androgen receptor protein downregulation. |
| PC-26984 |
BAS-2
HDAC6 inhibitor
|
BAS-2 is a potent, highly selective HDAC6 inhibitor with IC50 of 760 nM (hHDAC6). |
| PC-26983 |
(±)-trans-BAS-2
HDAC6 inhibitor
|
(±)-trans-BAS-2 is a potent, highly selective HDAC6 inhibitor with IC50 of 462 nM (hHDAC6), is more active than cis-BAS-2 (IC50=16.9 uM). |
| PC-26932 |
SM-06-09
HDAC6 inhibitor
|
SM-06-09 is a highly potent, selective HDAC6 inhibitor with IC50 of 0.49 nM, displays 35-fold selectivity over HDAC10 and >100-fold over all other HDACs. |
| PC-26795 |
W2A-28
class I HDAC inhibitor, Wnt/β-catenin activator
|
W2A-28 is a dual modulator of class I HDACs and Wnt/β-catenin signaling, inhibits HDAC1, 2 and 3 with IC50 of 0.51 μM, 0.68 μM and 0.22 μM, respectively, activates Wnt/β-catenin signaling with EC50 of 1.61 μM in Wnt-3A-expressing HEK293 cells. |
| PC-26518 |
3-Cl BA
HDAC inhibitor
|
3-Cl BA is a potent HDAC inhibitor, significantly enhances epithelial barrier formation and wound healing in vitro. |
| PC-26373 |
CDC1011
UCP1 activator, HDAC inhibitor
|
CDC1011 is a small molecule uncoupling protein 1 (UCP1) activator, significantly upregulates the transcriptional expression of UCP1 in differentiated SW872 adipocytes, functions as an HDAC inhibitor. |
| PC-26251 |
AMC-3-030
HDAC/proteasome inhibitor
|
AMC-3-030 is a potent, dual HDAC6/proteasome inhibitor with IC50 of 884 nM for HDAC6 and IC50 of 4.17 nM in cell-free 20S proteasomal chymotrypsin-like activity assay. |
| PC-26231 |
Scriptaid
HDAC inhibitor
|
Scriptaid (Scriptide, GCK1026) is a potent small molecule histone deacetylase (HDAC) inhibitor. |
| PC-26230 |
Pyroxamide
HDAC inhibitor
|
Pyroxamide is a potent inhibitor of HDAC with IC50 of 100 nM for HDAC1, causes the accumulation of acetylated core histones in murine erythroleukemia (MEL) cells. |
| PC-26229 |
VS-186B
HDAC inhibitor
|
VS-186B is a small molecule HDAC inhibitor with IC50 of 2.5 uM, inhibits Class I and II HDACs in a dose-dependent manner. |
