Valproic acid sodium salt |CAS:1069-66-5 Probechem Biochemicals

Chemical Structure : Valproic acid sodium salt

CAS No.: 1069-66-5

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Valproic acid sodium salt (Sodium Valproate)

货号: PC-42671Not For Human Use, Lab Use Only.

Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.

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500 mg	￥580	In stock
1 g	￥880	In stock
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生物&药学活性

Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
Valproic acid induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from AML patients.
Valproic acid reduces tumor growth and metastasis formation in animal model.

物理化学性质&存储条件

分子量	166.1933
分子式	C8H15NaO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	H2O: ≥ 48 mg/mL
Chemical Name/SMILES	Pentanoic acid, 2-propyl-, sodium salt (1:1)

参考文献

1. Krämer OH, et al. EMBO J. 2003 Jul 1;22(13):3411-20.

2. Göttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.

3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.

Valproic acid sodium salt (Sodium Valproate)

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物理化学性质&存储条件

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Valproic acid sodium salt (Sodium Valproate)

生物&药学活性

物理化学性质&存储条件

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