| Cat. No. |
Product Name |
Information |
| PC-42249 |
CXD101
class I HDAC inhibitor
|
Zabadinostat (CXD101) is a potent, selective and orally active class I HDAC inhibitor with IC50s of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively, has no activity against class II HDACs. |
| PC-42671 |
Valproic acid sodium salt
HDAC inhibitor
|
Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42670 |
Valproic acid
HDAC inhibitor
|
Valproic acid is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42421 |
EDO-S101
HDAC inhibitor, DNA alkylator
|
EDO-S101 (Tinostamustine) is a fusion molecule comprising of the alkylator bendamustine and the HDAC-inhibitor vorinostat. |
| PC-42767 |
Abexinostat
HDAC inhibitor
|
PCI-24781 (Abexinostat, CRA 024781) is a broad spectrum HDAC inhibitor, inhibits pure recombinant HDAC1 with Ki of 7 nM. |
| PC-42126 |
HDACi-4b
HDAC inhibitor
|
A benzamide-type HDAC inhibitor with IC50 of 78 uM for changes of FXN mRNA in affected GM15850 cells. |
| PC-27750 |
BHC-13
HDAC8 inhibitor
|
BHC-13 is a potent, selective HDAC8 inhibitor. |
| PC-27749 |
BHC-10
HDAC8 inhibitor
|
BHC-10 is a potent, selective HDAC8 inhibitor. |
| PC-27747 |
HDAC8 inhibitor Compound 4
HDAC8 inhibitor
|
HDAC8 inhibitor Compound 4 is a potent and selective HDAC8 inhibitor with IC50 of 90 nM, weakly inhibit HDAC1, HDAC2, HDAC6 with IC50 of 1.7 uM, 3.9 uM and >50 uM. |
| PC-27700 |
MC2625
HDAC inhibitor
|
MC2625 is a potent histone deacetylase (HDAC) inhibitor, shows selective HDAC3 and HDAC6 inhibition with IC50 of 80 nM and 11 nM respectively, also potently reactivate HIV from latency with EC50 of 350 nM. |
| PC-27055 |
HDAC6 inhibitor 7b
HDAC6 inhibitor
|
HDAC6 inhibitor 7d is a potent, isoform-selective HDAC6 inhibitor with IC50 of 0.87 nM, shows >500- and >3000-fold selectivity over HDAC8 and HDAC1 respectively. |
| PC-27054 |
HDAC6 inhibitor 4d
HDAC6 inhibitor
|
HDAC6 inhibitor 4d (Nexturastat B) is a potent, isoform-selective HDAC6 inhibitor with IC50 of 1.6 nM, shows >500-fold selectivity over HDAC1. |
