| Cat. No. |
Product Name |
Information |
| PC-45089 |
MC1568
class IIa HDAC inhibitor
|
MC1568 is a potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A. |
| PC-42902 |
Entinostat
class I HDAC inhibitor
|
Entinostat (MS275) is a potent and selective class I HDACs inhibitor with IC50 of 243/453/248 nM for HDAC1/2/3. |
| PC-45619 |
BML-210
HDAC inhibitor
|
BML-210 is a small molecule histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM. |
| PC-42249 |
CXD101
class I HDAC inhibitor
|
Zabadinostat (CXD101) is a potent, selective and orally active class I HDAC inhibitor with IC50s of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively, has no activity against class II HDACs. |
| PC-42671 |
Valproic acid sodium salt
HDAC inhibitor
|
Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42670 |
Valproic acid
HDAC inhibitor
|
Valproic acid is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42421 |
EDO-S101
HDAC inhibitor, DNA alkylator
|
EDO-S101 (Tinostamustine) is a fusion molecule comprising of the alkylator bendamustine and the HDAC-inhibitor vorinostat. |
| PC-42767 |
Abexinostat
HDAC inhibitor
|
PCI-24781 (Abexinostat, CRA 024781) is a broad spectrum HDAC inhibitor, inhibits pure recombinant HDAC1 with Ki of 7 nM. |
| PC-42126 |
HDACi-4b
HDAC inhibitor
|
A benzamide-type HDAC inhibitor with IC50 of 78 uM for changes of FXN mRNA in affected GM15850 cells. |
| PC-26932 |
SM-06-09
HDAC6 inhibitor
|
SM-06-09 is a highly potent, selective HDAC6 inhibitor with IC50 of 0.49 nM, displays 35-fold selectivity over HDAC10 and >100-fold over all other HDACs. |
| PC-26795 |
W2A-28
class I HDAC inhibitor, Wnt/β-catenin activator
|
W2A-28 is a dual modulator of class I HDACs and Wnt/β-catenin signaling, inhibits HDAC1, 2 and 3 with IC50 of 0.51 μM, 0.68 μM and 0.22 μM, respectively, activates Wnt/β-catenin signaling with EC50 of 1.61 μM in Wnt-3A-expressing HEK293 cells. |
| PC-26710 |
SP108
HDAC3 inhibitor
|
SP108 is a potent, selective and brain-permeable HDAC3 inhibitor with IC50 of 15.41 nM, shows 18.72-, 34.65-, >100-, >1000-, >1000-, and >1000-fold selectivity over HDAC1, HDAC2, HDAC8, HDAC6, HDAC4, and HDAC5, respectively. |
