| Cat. No. |
Product Name |
Information |
| PC-42902 |
Entinostat
class I HDAC inhibitor
|
Entinostat (MS275) is a potent and selective class I HDACs inhibitor with IC50 of 243/453/248 nM for HDAC1/2/3. |
| PC-45619 |
BML-210
HDAC inhibitor
|
BML-210 is a small molecule histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM. |
| PC-42249 |
CXD101
class I HDAC inhibitor
|
Zabadinostat (CXD101) is a potent, selective and orally active class I HDAC inhibitor with IC50s of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively, has no activity against class II HDACs. |
| PC-42671 |
Valproic acid sodium salt
HDAC inhibitor
|
Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42670 |
Valproic acid
HDAC inhibitor
|
Valproic acid is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42421 |
EDO-S101
HDAC inhibitor, DNA alkylator
|
EDO-S101 (Tinostamustine) is a fusion molecule comprising of the alkylator bendamustine and the HDAC-inhibitor vorinostat. |
| PC-42767 |
Abexinostat
HDAC inhibitor
|
PCI-24781 (Abexinostat, CRA 024781) is a broad spectrum HDAC inhibitor, inhibits pure recombinant HDAC1 with Ki of 7 nM. |
| PC-42126 |
HDACi-4b
HDAC inhibitor
|
A benzamide-type HDAC inhibitor with IC50 of 78 uM for changes of FXN mRNA in affected GM15850 cells. |
| PC-26064 |
UVI5008
Epigenetic inhibitor
|
UVI5008 is a small molecule epigenetic modifier/modulator that inhibits histone deacetylases, sirtuins, and DNA methyltransferases, affects the death receptor (DR) pathway and reactive oxygen species (ROS) production in cancer cells. |
| PC-25935 |
Colrestat
class I HDAC inhibitor
|
Colrestat is a potent, selective inhibitor of class I histone deacetylases (HDACs) with IC50 of 41.2 nM, 52.5 nM and 74.3 nM for HDAC1, HDAC2 and HDAC3 respectively. |
| PC-25904 |
Mesinostat
HDAC6 inhibitor
|
Mesinostat is a potent and selective HDAC6 inhibitor with IC50 of 7.7 nM, >200-fold selective over HDAC1. |
| PC-25868 |
EKZ-438
HDAC6 inhibitor
|
EKZ-438 is a potent, selective, CNS-penetrant and orally bioavailable HDAC6 inhibitor with IC50 of 12 nM, >8,500-fold selectivity for HDAC6 versus all other HDAC6 paralogs. |
