SK-7041 |CAS:617690-98-9 Probechem Biochemicals

Chemical Structure : SK-7041

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SK-7041 (SK7041;SK 7041)

货号: PC-70233Not For Human Use, Lab Use Only.

SK-7041 is a potent HDAC inhibitor with IC50 of 172 nM, preferentially inhibit class I HDAC1 and HDAC2 than the other HDAC isotypes.

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生物&药学活性

SK-7041 is a potent HDAC inhibitor with IC50 of 172 nM, preferentially inhibit class I HDAC1 and HDAC2 than the other HDAC isotypes.
SK-7041 exhibits potent antiproliferative activity against various human cancer cells in vitro, and reduces the growth of implanted human tumors in nude mice.

物理化学性质&存储条件

分子量	339.395
分子式	C19H21N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-4-(dimethylamino)-N-(4-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzyl)benzamide

参考文献

1. Ryu JK, et al. Cancer Lett. 2006 Jun 8;237(1):143-54.

2. Park JH, et al. Clin Cancer Res. 2004 Aug 1;10(15):5271-81.

3. Lee KW, et al. Anticancer Res. 2006 Sep-Oct;26(5A):3429-38.

SK-7041 (SK7041;SK 7041)

生物&药学活性

物理化学性质&存储条件

参考文献

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SK-7041 (SK7041;SK 7041)

生物&药学活性

物理化学性质&存储条件

参考文献

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