Chemical Structure : SB-379278A
CAS No.: 146366-04-3
货号: PC-60135Not For Human Use, Lab Use Only.
SB-379278A is potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.
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SB-379278A is potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.
分子量 | 177.225 | |
分子式 | C8H7N3S | |
外观性状 | Solid | |
储存条件 |
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|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
4-Pyridin-4-yl-1,3-dihydroimidazole-2-thione |
1. Hu E, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):720-8.
2. Chakrabarti A, et al. Future Med Chem. 2016 Sep;8(13):1609-34.
3. Heimburg T, et al. J Med Chem. 2017 Dec 15. doi: 10.1021/acs.jmedchem.7b01447.
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